This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3j6f
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3j6f]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J6F FirstGlance]. <br> | <table><tr><td colspan='2'>[[3j6f]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J6F FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6e|3j6e]], [[3j6g|3j6g]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6e|3j6e]], [[3j6g|3j6g]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j6f RCSB], [http://www.ebi.ac.uk/pdbsum/3j6f PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j6f RCSB], [http://www.ebi.ac.uk/pdbsum/3j6f PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TBA1A_PIG TBA1A_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_PIG TBB_PIG]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 13: | Line 15: | ||
High-Resolution Microtubule Structures Reveal the Structural Transitions in alphabeta-Tubulin upon GTP Hydrolysis.,Alushin GM, Lander GC, Kellogg EH, Zhang R, Baker D, Nogales E Cell. 2014 May 22;157(5):1117-29. doi: 10.1016/j.cell.2014.03.053. PMID:24855948<ref>PMID:24855948</ref> | High-Resolution Microtubule Structures Reveal the Structural Transitions in alphabeta-Tubulin upon GTP Hydrolysis.,Alushin GM, Lander GC, Kellogg EH, Zhang R, Baker D, Nogales E Cell. 2014 May 22;157(5):1117-29. doi: 10.1016/j.cell.2014.03.053. PMID:24855948<ref>PMID:24855948</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 20: | Line 22: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Alushin, G M | + | [[Category: Alushin, G M]] |
| - | [[Category: Baker, D | + | [[Category: Baker, D]] |
| - | [[Category: Kellogg, E H | + | [[Category: Kellogg, E H]] |
| - | [[Category: Lander, G C | + | [[Category: Lander, G C]] |
| - | [[Category: Nogales, E | + | [[Category: Nogales, E]] |
| - | [[Category: Zhang, R | + | [[Category: Zhang, R]] |
[[Category: Dynamic]] | [[Category: Dynamic]] | ||
[[Category: Gdp]] | [[Category: Gdp]] | ||
[[Category: Microtubule]] | [[Category: Microtubule]] | ||
[[Category: Structural protein]] | [[Category: Structural protein]] | ||
Revision as of 08:36, 25 December 2014
Minimized average structure of GDP-bound dynamic microtubules
| |||||||||||
Categories: Sus scrofa | Alushin, G M | Baker, D | Kellogg, E H | Lander, G C | Nogales, E | Zhang, R | Dynamic | Gdp | Microtubule | Structural protein
