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1t4o

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1t4o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T4O FirstGlance]. <br>
<table><tr><td colspan='2'>[[1t4o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T4O FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t4n|1t4n]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t4n|1t4n]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNT1, YMR239C, YM9408.01C, YM9959.21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNT1, YMR239C, YM9408.01C, YM9959.21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_III Ribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.3 3.1.26.3] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_III Ribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.3 3.1.26.3] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t4o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t4o RCSB], [http://www.ebi.ac.uk/pdbsum/1t4o PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t4o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t4o RCSB], [http://www.ebi.ac.uk/pdbsum/1t4o PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RNT1_YEAST RNT1_YEAST]] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease|Ribonuclease]]
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*[[Temp|Temp]]
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*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Ribonuclease III]]
[[Category: Ribonuclease III]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Ares, M.]]
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[[Category: Ares, M]]
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[[Category: Edwards, T E.]]
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[[Category: Edwards, T E]]
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[[Category: Godin, K S.]]
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[[Category: Godin, K S]]
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[[Category: Graille, M.]]
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[[Category: Graille, M]]
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[[Category: Leeper, T C.]]
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[[Category: Leeper, T C]]
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[[Category: Leulliot, N.]]
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[[Category: Leulliot, N]]
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[[Category: Nagel, R J.]]
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[[Category: Nagel, R J]]
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[[Category: Quevillon-Cheruel, S.]]
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[[Category: Quevillon-Cheruel, S]]
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[[Category: Rozenkrants, N.]]
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[[Category: Rozenkrants, N]]
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[[Category: Sigurdsson, S T.]]
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[[Category: Sigurdsson, S T]]
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[[Category: Tilbeurgh, H van.]]
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[[Category: Tilbeurgh, H van]]
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[[Category: Varani, G.]]
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[[Category: Varani, G]]
[[Category: Dsrbd]]
[[Category: Dsrbd]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Rna-binding]]
[[Category: Rna-binding]]
[[Category: Rnt1p]]
[[Category: Rnt1p]]

Revision as of 08:38, 25 December 2014

Crystal structure of rnt1p dsRBD

1t4o, resolution 2.50Å

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