2ew2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ew2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EW2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ew2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EW2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [http://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ew2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ew2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ew2 PDBsum], [http://www.topsan.org/Proteins/MCSG/2ew2 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q831Q5_ENTFA Q831Q5_ENTFA]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).[RuleBase:RU003776]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: 2-dehydropantoate 2-reductase]]
[[Category: 2-dehydropantoate 2-reductase]]
[[Category: Enterococcus faecalis v583]]
[[Category: Enterococcus faecalis v583]]
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[[Category: Clancy, S.]]
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[[Category: Clancy, S]]
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[[Category: Collart, F.]]
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[[Category: Collart, F]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Kim, Y.]]
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[[Category: Kim, Y]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Moy, S.]]
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[[Category: Moy, S]]
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[[Category: Zhou, M.]]
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[[Category: Zhou, M]]
[[Category: Alpha-beta structure]]
[[Category: Alpha-beta structure]]
[[Category: Alpha-structure]]
[[Category: Alpha-structure]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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Revision as of 10:29, 25 December 2014

Crystal Structure of the Putative 2-Dehydropantoate 2-Reductase from Enterococcus faecalis

2ew2, resolution 2.00Å

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