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2vb8
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vb8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2vb8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=TLM:THIOLACTOMYCIN'>TLM</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=TLM:THIOLACTOMYCIN'>TLM</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f91|1f91]], [[1fj8|1fj8]], [[1g5x|1g5x]], [[1h4f|1h4f]], [[2aq7|2aq7]], [[2aqb|2aqb]], [[2buh|2buh]], [[2bui|2bui]], [[2byx|2byx]], [[2bz3|2bz3]], [[1dd8|1dd8]], [[1ek4|1ek4]], [[1fj4|1fj4]], [[2byw|2byw]], [[2byy|2byy]], [[2byz|2byz]], [[2bz4|2bz4]], [[2vb7|2vb7]], [[2vb9|2vb9]], [[2vba|2vba]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f91|1f91]], [[1fj8|1fj8]], [[1g5x|1g5x]], [[1h4f|1h4f]], [[2aq7|2aq7]], [[2aqb|2aqb]], [[2buh|2buh]], [[2bui|2bui]], [[2byx|2byx]], [[2bz3|2bz3]], [[1dd8|1dd8]], [[1ek4|1ek4]], [[1fj4|1fj4]], [[2byw|2byw]], [[2byy|2byy]], [[2byz|2byz]], [[2bz4|2bz4]], [[2vb7|2vb7]], [[2vb9|2vb9]], [[2vba|2vba]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier-protein_synthase_I Beta-ketoacyl-acyl-carrier-protein synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier-protein_synthase_I Beta-ketoacyl-acyl-carrier-protein synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FABB_ECOLI FABB_ECOLI]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | [[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Bailly, J | + | [[Category: Bailly, J]] |
| - | [[Category: Hennig, M | + | [[Category: Hennig, M]] |
| - | [[Category: Pappenberger, G | + | [[Category: Pappenberger, G]] |
| - | [[Category: Schulz-Gasch, T | + | [[Category: Schulz-Gasch, T]] |
[[Category: Acyltransferase]] | [[Category: Acyltransferase]] | ||
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
Revision as of 11:18, 25 December 2014
BETA-KETOACYL-ACP SYNTHASE I (KAS) FROM E. COLI WITH BOUND INHIBITOR THIOLACTOMYCIN
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