1nov
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1nov]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Nodamura_virus Nodamura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NOV FirstGlance]. <br> | <table><tr><td colspan='2'>[[1nov]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Nodamura_virus Nodamura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NOV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nov OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nov RCSB], [http://www.ebi.ac.uk/pdbsum/1nov PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nov OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nov RCSB], [http://www.ebi.ac.uk/pdbsum/1nov PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/COAT_NODAV COAT_NODAV]] Capsid protein alpha self-assembles to form an icosahedral procapsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins trimers. The capsid encapsulates the two genomic RNAs. Capsid maturation occurs via autoproteolytic cleavage of capsid protein alpha generating capsid protein beta and the membrane-active peptide gamma (By similarity). Peptide gamma: membrane-permeabilizing peptide produced by virus maturation, thereby creating the infectious virion. After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Nodamura virus]] | [[Category: Nodamura virus]] | ||
| - | [[Category: Johnson, J E | + | [[Category: Johnson, J E]] |
| - | [[Category: Natarajan, P | + | [[Category: Natarajan, P]] |
[[Category: Coat protein]] | [[Category: Coat protein]] | ||
[[Category: Icosahedral virus]] | [[Category: Icosahedral virus]] | ||
[[Category: Insect virus]] | [[Category: Insect virus]] | ||
| - | [[Category: Nodamura virus]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
Revision as of 13:01, 25 December 2014
NODAMURA VIRUS
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