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2ywf
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ywf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus_vf5 Aquifex aeolicus vf5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWF FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ywf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus_vf5 Aquifex aeolicus vf5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YWF FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ywe|2ywe]], [[2ywg|2ywg]], [[2ywh|2ywh]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ywe|2ywe]], [[2ywg|2ywg]], [[2ywh|2ywh]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lepA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 Aquifex aeolicus VF5])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lepA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 Aquifex aeolicus VF5])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywf RCSB], [http://www.ebi.ac.uk/pdbsum/2ywf PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywf TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ywf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ywf RCSB], [http://www.ebi.ac.uk/pdbsum/2ywf PDBsum], [http://www.topsan.org/Proteins/RSGI/2ywf TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEPA_AQUAE LEPA_AQUAE]] Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aquifex aeolicus vf5]] | [[Category: Aquifex aeolicus vf5]] | ||
| - | [[Category: Hanawa-Suetsugu, K | + | [[Category: Hanawa-Suetsugu, K]] |
| - | [[Category: Kaminishi, T | + | [[Category: Kaminishi, T]] |
| - | [[Category: Kawazoe, M | + | [[Category: Kawazoe, M]] |
| - | [[Category: Nakayama-Ushikoshi, R | + | [[Category: Nakayama-Ushikoshi, R]] |
| - | [[Category: Nishino, A | + | [[Category: Nishino, A]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Shirouzu, M | + | [[Category: Shirouzu, M]] |
| - | [[Category: Takemoto, C | + | [[Category: Takemoto, C]] |
| - | [[Category: Terada, T | + | [[Category: Terada, T]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Beta-barrel]] | [[Category: Beta-barrel]] | ||
[[Category: Ferredoxin-like domain]] | [[Category: Ferredoxin-like domain]] | ||
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[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Translation]] | [[Category: Translation]] | ||
Revision as of 13:43, 25 December 2014
Crystal structure of GMPPNP-bound LepA from Aquifex aeolicus
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Categories: Aquifex aeolicus vf5 | Hanawa-Suetsugu, K | Kaminishi, T | Kawazoe, M | Nakayama-Ushikoshi, R | Nishino, A | Structural genomic | Shirouzu, M | Takemoto, C | Terada, T | Yokoyama, S | Beta-barrel | Ferredoxin-like domain | G domain | National project on protein structural and functional analyse | Nppsfa | Rsgi | Translation
