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1htl
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1htl]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HTL FirstGlance]. <br> | <table><tr><td colspan='2'>[[1htl]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HTL FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1htl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1htl RCSB], [http://www.ebi.ac.uk/pdbsum/1htl PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1htl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1htl RCSB], [http://www.ebi.ac.uk/pdbsum/1htl PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ELBP_ECOLI ELBP_ECOLI]] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. [[http://www.uniprot.org/uniprot/ELAP_ECOLI ELAP_ECOLI]] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Hol, W G.J | + | [[Category: Hol, W G.J]] |
| - | [[Category: Merritt, E A | + | [[Category: Merritt, E A]] |
[[Category: Enterotoxin]] | [[Category: Enterotoxin]] | ||
Revision as of 14:48, 25 December 2014
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
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