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4a69
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a69 RCSB], [http://www.ebi.ac.uk/pdbsum/4a69 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a69 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a69 RCSB], [http://www.ebi.ac.uk/pdbsum/4a69 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NCOR2_HUMAN NCOR2_HUMAN]] Transcriptional corepressor of NR4A2/NURR1 and acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state (By similarity). Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 15:25, 25 December 2014
Structure of HDAC3 bound to corepressor and inositol tetraphosphate
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