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2ydd
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ydd' size='340' side='right' caption='[[2ydd]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2ydd' size='340' side='right' caption='[[2ydd]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ydd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDD OCA]. <br> | + | <table><tr><td colspan='2'>[[2ydd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YDD FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2AM:ADENOSINE-2-MONOPHOSPHATE'>2AM</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2AM:ADENOSINE-2-MONOPHOSPHATE'>2AM</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xmi|2xmi]], [[2y1p|2y1p]], [[2y3x|2y3x]], [[2ydc|2ydc]], [[2ydb|2ydb]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xmi|2xmi]], [[2y1p|2y1p]], [[2y3x|2y3x]], [[2ydc|2ydc]], [[2ydb|2ydb]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2',3'-cyclic-nucleotide_3'-phosphodiesterase 2',3'-cyclic-nucleotide 3'-phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.37 3.1.4.37] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ydd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ydd RCSB], [http://www.ebi.ac.uk/pdbsum/2ydd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ydd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ydd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ydd RCSB], [http://www.ebi.ac.uk/pdbsum/2ydd PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CN37_MOUSE CN37_MOUSE]] May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.<ref>PMID:22393399</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Myelin 2',3'-cyclic nucleotide 3'-phosphodiesterase: active-site ligand binding and molecular conformation.,Myllykoski M, Raasakka A, Han H, Kursula P PLoS One. 2012;7(2):e32336. Epub 2012 Feb 29. PMID:22393399<ref>PMID:22393399</ref> | Myelin 2',3'-cyclic nucleotide 3'-phosphodiesterase: active-site ligand binding and molecular conformation.,Myllykoski M, Raasakka A, Han H, Kursula P PLoS One. 2012;7(2):e32336. Epub 2012 Feb 29. PMID:22393399<ref>PMID:22393399</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 22: | Line 27: | ||
[[Category: 2',3'-cyclic-nucleotide 3'-phosphodiesterase]] | [[Category: 2',3'-cyclic-nucleotide 3'-phosphodiesterase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Kursula, P | + | [[Category: Kursula, P]] |
| - | [[Category: Myllykoski, M | + | [[Category: Myllykoski, M]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Myelin]] | [[Category: Myelin]] | ||
[[Category: Nervous system]] | [[Category: Nervous system]] | ||
Revision as of 15:34, 25 December 2014
Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic AMP
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