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2woz

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2woz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2woz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2woz RCSB], [http://www.ebi.ac.uk/pdbsum/2woz PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2woz RCSB], [http://www.ebi.ac.uk/pdbsum/2woz PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KBTBA_RAT KBTBA_RAT]] Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Required for pseudopod elongation in transformed cells.<ref>PMID:10713668</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Gray, C H.]]
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[[Category: Gray, C H]]
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[[Category: Mcgarry, L C.]]
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[[Category: Mcgarry, L C]]
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[[Category: Ozanne, B W.]]
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[[Category: Ozanne, B W]]
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[[Category: Riboldi-Tunnicliffe, A.]]
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[[Category: Riboldi-Tunnicliffe, A]]
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[[Category: Spence, H J.]]
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[[Category: Spence, H J]]
[[Category: Cell projection]]
[[Category: Cell projection]]
[[Category: Cytoskeleton]]
[[Category: Cytoskeleton]]

Revision as of 15:41, 25 December 2014

THE NOVEL BETA-PROPELLER OF THE BTB-KELCH PROTEIN KRP1 PROVIDES THE BINDING SITE FOR LASP-1 THAT IS NECESSARY FOR PSEUDOPODIA EXTENSION

2woz, resolution 2.00Å

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