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1rl5
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1rl5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RL5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1rl5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RL5 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rl5 RCSB], [http://www.ebi.ac.uk/pdbsum/1rl5 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rl5 RCSB], [http://www.ebi.ac.uk/pdbsum/1rl5 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CX1_NAJOX CX1_NAJOX]] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type). CTI interacts with membrane weaker than CTII. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Naja oxiana]] | [[Category: Naja oxiana]] | ||
| - | [[Category: Arseniev, A S | + | [[Category: Arseniev, A S]] |
| - | [[Category: Dubinnyi, M A | + | [[Category: Dubinnyi, M A]] |
| - | [[Category: Dubovskii, P V | + | [[Category: Dubovskii, P V]] |
| - | [[Category: Pustovalova, Y E | + | [[Category: Pustovalova, Y E]] |
| - | [[Category: Utkin, Y N | + | [[Category: Utkin, Y N]] |
[[Category: Bound water]] | [[Category: Bound water]] | ||
[[Category: Cis/trans isomerization]] | [[Category: Cis/trans isomerization]] | ||
Revision as of 15:51, 25 December 2014
NMR structure with tightly bound water molecule of cytotoxin I from Naja oxiana in aqueous solution (major form)
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