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4ebt

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ebt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EBT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ebt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EBT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ebs|4ebs]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ebs|4ebs]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ebt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ebt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ebt RCSB], [http://www.ebi.ac.uk/pdbsum/4ebt PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ebt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ebt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ebt RCSB], [http://www.ebi.ac.uk/pdbsum/4ebt PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
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[[Category: Dube, D.]]
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[[Category: Dube, D]]
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[[Category: Kaur, P.]]
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[[Category: Kaur, P]]
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[[Category: Sharma, P.]]
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[[Category: Sharma, P]]
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[[Category: Sharma, S.]]
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[[Category: Sharma, S]]
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[[Category: Singh, T P.]]
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[[Category: Singh, T P]]
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[[Category: Sinha, M.]]
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[[Category: Sinha, M]]
[[Category: Antibiotic]]
[[Category: Antibiotic]]
[[Category: Antimicrobial]]
[[Category: Antimicrobial]]

Revision as of 16:01, 25 December 2014

Structural studies on the molecular interactions between camel peptidoglycan recognition protein, CPGRP-S and peptidoglycan moieties, N-acetylglucosamine and N-acetylmuramic acid

4ebt, resolution 2.60Å

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OCA

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