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1jbr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jbr]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_restrictus Aspergillus restrictus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JBR FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jbr]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_restrictus Aspergillus restrictus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JBR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A23:ADENOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>A23</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A23:ADENOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>A23</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aqz|1aqz]], [[430d|430d]], [[480d|480d]], [[483d|483d]], [[1jbs|1jbs]], [[1jbt|1jbt]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aqz|1aqz]], [[430d|430d]], [[480d|480d]], [[483d|483d]], [[1jbs|1jbs]], [[1jbt|1jbt]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jbr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jbr RCSB], [http://www.ebi.ac.uk/pdbsum/1jbr PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jbr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jbr RCSB], [http://www.ebi.ac.uk/pdbsum/1jbr PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RNMG_ASPRE RNMG_ASPRE]] This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aspergillus restrictus]] | [[Category: Aspergillus restrictus]] | ||
| - | [[Category: Correll, C C | + | [[Category: Correll, C C]] |
| - | [[Category: Gerczei, T | + | [[Category: Gerczei, T]] |
| - | [[Category: Glover, L | + | [[Category: Glover, L]] |
| - | [[Category: Yang, X | + | [[Category: Yang, X]] |
[[Category: Base flipping]] | [[Category: Base flipping]] | ||
[[Category: Hydrolase-rna complex]] | [[Category: Hydrolase-rna complex]] | ||
Revision as of 16:49, 25 December 2014
Crystal Structure of the Ribotoxin Restrictocin and a 31-mer SRD RNA Inhibitor
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