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3lmk
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3lmk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LMK FirstGlance]. <br> | <table><tr><td colspan='2'>[[3lmk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LMK FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPRC1E, GRM5, MGLUR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPRC1E, GRM5, MGLUR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lmk RCSB], [http://www.ebi.ac.uk/pdbsum/3lmk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lmk RCSB], [http://www.ebi.ac.uk/pdbsum/3lmk PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GRM5_HUMAN GRM5_HUMAN]] Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Cossar, D | + | [[Category: Cossar, D]] |
| - | [[Category: Dobrovetsky, E | + | [[Category: Dobrovetsky, E]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Khutoreskaya, G | + | [[Category: Khutoreskaya, G]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Seitova, A | + | [[Category: Seitova, A]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Dimerization]] | [[Category: Dimerization]] | ||
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[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transducer]] | [[Category: Transducer]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
Revision as of 17:00, 25 December 2014
Ligand Binding Domain of Metabotropoc glutamate receptor mGluR5 complexed with glutamate
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Categories: Homo sapiens | Arrowsmith, C H | Bochkarev, A | Bountra, C | Cossar, D | Dobrovetsky, E | Edwards, A M | Khutoreskaya, G | Structural genomic | Seitova, A | Weigelt, J | Cell membrane | Dimerization | G-protein coupled receptor | Glutamate receptor | Glutamic acid | Glycoprotein | Membrane | Mglur1 | Receptor | Sgc | Signaling protein | Transducer | Transmembrane
