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4js2

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{{STRUCTURE_4js2| PDB=4js2 | SCENE= }}
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==Crystal structure of human Beta-galactoside alpha-2,6-sialyltransferase 1 in complex with CMP==
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===Crystal structure of human Beta-galactoside alpha-2,6-sialyltransferase 1 in complex with CMP===
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<StructureSection load='4js2' size='340' side='right' caption='[[4js2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4js2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JS2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4js1|4js1]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ST6GAL1, SIAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactoside_alpha-2,6-sialyltransferase Beta-galactoside alpha-2,6-sialyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.99.1 2.4.99.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4js2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4js2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4js2 RCSB], [http://www.ebi.ac.uk/pdbsum/4js2 PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/SIAT1_HUMAN SIAT1_HUMAN]] Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.<ref>PMID:21081508</ref>
[[http://www.uniprot.org/uniprot/SIAT1_HUMAN SIAT1_HUMAN]] Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.<ref>PMID:21081508</ref>
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== References ==
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==About this Structure==
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<references/>
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[[4js2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JS2 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Beta-galactoside alpha-2,6-sialyltransferase]]
[[Category: Beta-galactoside alpha-2,6-sialyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Benz, J.]]
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[[Category: Benz, J]]
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[[Category: Engel, A M.]]
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[[Category: Engel, A M]]
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[[Category: Greif, M.]]
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[[Category: Greif, M]]
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[[Category: Kuhn, B.]]
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[[Category: Kuhn, B]]
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[[Category: Rudolph, M G.]]
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[[Category: Rudolph, M G]]
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[[Category: Sobek, H.]]
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[[Category: Sobek, H]]
[[Category: Endoplasmatic reticulum]]
[[Category: Endoplasmatic reticulum]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]

Revision as of 17:07, 25 December 2014

Crystal structure of human Beta-galactoside alpha-2,6-sialyltransferase 1 in complex with CMP

4js2, resolution 2.30Å

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