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1sg4

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sg4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SG4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sg4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SG4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dodecenoyl-CoA_isomerase Dodecenoyl-CoA isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.8 5.3.3.8] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dodecenoyl-CoA_isomerase Dodecenoyl-CoA isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.8 5.3.3.8] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sg4 RCSB], [http://www.ebi.ac.uk/pdbsum/1sg4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sg4 RCSB], [http://www.ebi.ac.uk/pdbsum/1sg4 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ECI1_HUMAN ECI1_HUMAN]] Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Dodecenoyl-CoA isomerase]]
[[Category: Dodecenoyl-CoA isomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hiltunen, J K.]]
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[[Category: Hiltunen, J K]]
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[[Category: Mursula, A M.]]
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[[Category: Mursula, A M]]
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[[Category: Novikov, D K.]]
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[[Category: Novikov, D K]]
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[[Category: Partanen, S T.]]
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[[Category: Partanen, S T]]
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[[Category: Popov, A N.]]
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[[Category: Popov, A N]]
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[[Category: Wierenga, R K.]]
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[[Category: Wierenga, R K]]
[[Category: Crotonase fold]]
[[Category: Crotonase fold]]
[[Category: Isomerase]]
[[Category: Isomerase]]

Revision as of 17:14, 25 December 2014

Crystal structure of human mitochondrial delta3-delta2-enoyl-CoA isomerase

1sg4, resolution 1.30Å

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