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2jhl

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jhl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JHL FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jhl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JHL FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SLB:5-N-ACETYL-BETA-D-NEURAMINIC+ACID'>SLB</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SLB:5-N-ACETYL-BETA-D-NEURAMINIC+ACID'>SLB</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jhh|2jhh]], [[2jhi|2jhi]], [[2jhk|2jhk]], [[2jhm|2jhm]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jhh|2jhh]], [[2jhi|2jhi]], [[2jhk|2jhk]], [[2jhm|2jhm]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jhl RCSB], [http://www.ebi.ac.uk/pdbsum/2jhl PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jhl RCSB], [http://www.ebi.ac.uk/pdbsum/2jhl PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FCN1_HUMAN FCN1_HUMAN]] Complement-activating lectin and pattern recognition receptor. Binds GlcNAc. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.<ref>PMID:20032467</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arlaud, G J.]]
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[[Category: Arlaud, G J]]
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[[Category: Gaboriaud, C.]]
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[[Category: Gaboriaud, C]]
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[[Category: Garlatti, V.]]
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[[Category: Garlatti, V]]
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[[Category: Gout, E.]]
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[[Category: Gout, E]]
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[[Category: Martin, L.]]
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[[Category: Martin, L]]
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[[Category: Reiser, J B.]]
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[[Category: Reiser, J B]]
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[[Category: Thielens, N M.]]
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[[Category: Thielens, N M]]
[[Category: Acidic ph]]
[[Category: Acidic ph]]
[[Category: Collagen]]
[[Category: Collagen]]

Revision as of 18:47, 25 December 2014

Structure of globular heads of M-ficolin complexed with sialic acid

2jhl, resolution 1.75Å

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