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2ny5
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ny5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NY5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ny5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NY5 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc1|1gc1]], [[1rzj|1rzj]], [[1rzk|1rzk]], [[2nxy|2nxy]], [[2nxz|2nxz]], [[2ny0|2ny0]], [[2ny1|2ny1]], [[2ny2|2ny2]], [[2ny3|2ny3]], [[2ny4|2ny4]], [[2ny6|2ny6]], [[2ny7|2ny7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc1|1gc1]], [[1rzj|1rzj]], [[1rzk|1rzk]], [[2nxy|2nxy]], [[2nxz|2nxz]], [[2ny0|2ny0]], [[2ny1|2ny1]], [[2ny2|2ny2]], [[2ny3|2ny3]], [[2ny4|2ny4]], [[2ny6|2ny6]], [[2ny7|2ny7]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ny5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ny5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ny5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ny5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ny5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ny5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ny5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ny5 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Arthos, J | + | [[Category: Arthos, J]] |
| - | [[Category: Burton, D R | + | [[Category: Burton, D R]] |
| - | [[Category: Dey, B | + | [[Category: Dey, B]] |
| - | [[Category: Dimitrov, D S | + | [[Category: Dimitrov, D S]] |
| - | [[Category: Hessell, A J | + | [[Category: Hessell, A J]] |
| - | [[Category: Kwong, P D | + | [[Category: Kwong, P D]] |
| - | [[Category: Nabel, G J | + | [[Category: Nabel, G J]] |
| - | [[Category: Ryk, D Van | + | [[Category: Ryk, D Van]] |
| - | [[Category: Sodroski, J | + | [[Category: Sodroski, J]] |
| - | [[Category: Wyatt, R | + | [[Category: Wyatt, R]] |
| - | [[Category: Xiang, S H | + | [[Category: Xiang, S H]] |
| - | [[Category: Xu, L | + | [[Category: Xu, L]] |
| - | [[Category: Yang, X | + | [[Category: Yang, X]] |
| - | [[Category: Zhang, M Y | + | [[Category: Zhang, M Y]] |
| - | [[Category: Zhou, T | + | [[Category: Zhou, T]] |
| - | [[Category: Zwick, M B | + | [[Category: Zwick, M B]] |
[[Category: Antibody]] | [[Category: Antibody]] | ||
[[Category: Cd4]] | [[Category: Cd4]] | ||
Revision as of 19:17, 25 December 2014
HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) Complexed with CD4 and Antibody 17b
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Categories: Homo sapiens | Human immunodeficiency virus 1 | Arthos, J | Burton, D R | Dey, B | Dimitrov, D S | Hessell, A J | Kwong, P D | Nabel, G J | Ryk, D Van | Sodroski, J | Wyatt, R | Xiang, S H | Xu, L | Yang, X | Zhang, M Y | Zhou, T | Zwick, M B | Antibody | Cd4 | Gp120 | Hiv | Viral protein-immune system complex
