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2z6b
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin== | |
| - | + | <StructureSection load='2z6b' size='340' side='right' caption='[[2z6b]], [[Resolution|resolution]] 3.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2z6b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z6B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEN:1-ETHYL-PYRROLIDINE-2,5-DIONE'>NEN</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4]), 27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z6b RCSB], [http://www.ebi.ac.uk/pdbsum/2z6b PDBsum]</span></td></tr> |
| - | [[2z6b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA]. | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VG05_BPT4 VG05_BPT4]] Tail-associated lysozyme essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. [[http://www.uniprot.org/uniprot/VG27_BPT4 VG27_BPT4]] Structural component of the baseplate. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/2z6b_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Lysozyme 3D structures|Lysozyme 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Enterobacteria phage t4]] | [[Category: Enterobacteria phage t4]] | ||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
| - | [[Category: Arisaka, F | + | [[Category: Arisaka, F]] |
| - | [[Category: Kanamaru, S | + | [[Category: Kanamaru, S]] |
| - | [[Category: Koshiyama, T | + | [[Category: Koshiyama, T]] |
| - | [[Category: Nagano, S | + | [[Category: Nagano, S]] |
| - | [[Category: Shiro, Y | + | [[Category: Shiro, Y]] |
| - | [[Category: Ueno, T | + | [[Category: Ueno, T]] |
| - | [[Category: Watanabe, Y | + | [[Category: Watanabe, Y]] |
| - | [[Category: Yokoi, N | + | [[Category: Yokoi, N]] |
[[Category: Antimicrobial]] | [[Category: Antimicrobial]] | ||
[[Category: Bacteriolytic enzyme]] | [[Category: Bacteriolytic enzyme]] | ||
Revision as of 20:02, 25 December 2014
Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin
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Categories: Enterobacteria phage t4 | Lysozyme | Arisaka, F | Kanamaru, S | Koshiyama, T | Nagano, S | Shiro, Y | Ueno, T | Watanabe, Y | Yokoi, N | Antimicrobial | Bacteriolytic enzyme | Glycosidase | Hydrolase | Hydrolase-structural protein complex | Late protein | Protein containing metal complex | Virion
