2z6b

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[[Image:2z6b.png|left|200px]]
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==Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin==
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<StructureSection load='2z6b' size='340' side='right' caption='[[2z6b]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
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{{STRUCTURE_2z6b| PDB=2z6b | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2z6b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z6B FirstGlance]. <br>
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===Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEN:1-ETHYL-PYRROLIDINE-2,5-DIONE'>NEN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4]), 27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z6b RCSB], [http://www.ebi.ac.uk/pdbsum/2z6b PDBsum]</span></td></tr>
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[[2z6b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6B OCA].
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/VG05_BPT4 VG05_BPT4]] Tail-associated lysozyme essential for localized hydrolysis of bacterial cell wall necessary for viral DNA injection. The needle-like gp5 protein punctures the outer cell membrane and then digests the peptidoglycan cell wall in the periplasmic space. [[http://www.uniprot.org/uniprot/VG27_BPT4 VG27_BPT4]] Structural component of the baseplate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/2z6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:018098245</ref><references group="xtra"/>
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[[Category: Enterobacteria phage t4]]
[[Category: Enterobacteria phage t4]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
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[[Category: Arisaka, F.]]
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[[Category: Arisaka, F]]
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[[Category: Kanamaru, S.]]
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[[Category: Kanamaru, S]]
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[[Category: Koshiyama, T.]]
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[[Category: Koshiyama, T]]
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[[Category: Nagano, S.]]
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[[Category: Nagano, S]]
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[[Category: Shiro, Y.]]
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[[Category: Shiro, Y]]
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[[Category: Ueno, T.]]
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[[Category: Ueno, T]]
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[[Category: Watanabe, Y.]]
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[[Category: Watanabe, Y]]
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[[Category: Yokoi, N.]]
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[[Category: Yokoi, N]]
[[Category: Antimicrobial]]
[[Category: Antimicrobial]]
[[Category: Bacteriolytic enzyme]]
[[Category: Bacteriolytic enzyme]]

Revision as of 20:02, 25 December 2014

Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin

2z6b, resolution 3.11Å

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