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2d8x

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D8X FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d8x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D8X FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIMS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIMS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d8x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d8x RCSB], [http://www.ebi.ac.uk/pdbsum/2d8x PDBsum], [http://www.topsan.org/Proteins/RSGI/2d8x TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d8x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d8x RCSB], [http://www.ebi.ac.uk/pdbsum/2d8x PDBsum], [http://www.topsan.org/Proteins/RSGI/2d8x TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PINC_HUMAN PINC_HUMAN]] Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi, F]]
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[[Category: Qin, X R.]]
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[[Category: Qin, X R]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Lim domain]]
[[Category: Lim domain]]
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[[Category: Nppsfa]]
[[Category: Nppsfa]]
[[Category: Pinch protein]]
[[Category: Pinch protein]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Structural protein]]
[[Category: Structural protein]]

Revision as of 20:14, 25 December 2014

Solution structure of the second LIM domain of particularly interesting new Cys-His protein (PINCH)

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