4gk6
From Proteopedia
(Difference between revisions)
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| - | + | ==X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus== | |
| - | + | <StructureSection load='4gk6' size='340' side='right' caption='[[4gk6]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4gk6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_abscessus_atcc_19977 Mycobacterium abscessus atcc 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GK6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GK6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dut, MAB_3003c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=561007 Mycobacterium abscessus ATCC 19977])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gk6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gk6 RCSB], [http://www.ebi.ac.uk/pdbsum/4gk6 PDBsum]</span></td></tr> |
| - | [[4gk6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_abscessus_atcc_19977 Mycobacterium abscessus atcc 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GK6 OCA]. | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B1MCW0_MYCA9 B1MCW0_MYCA9]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116][SAAS:SAAS00071014] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Mycobacterium abscessus atcc 19977]] | [[Category: Mycobacterium abscessus atcc 19977]] | ||
[[Category: DUTP diphosphatase]] | [[Category: DUTP diphosphatase]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: National institute of allergy and infectious disease]] | [[Category: National institute of allergy and infectious disease]] | ||
[[Category: Niaid]] | [[Category: Niaid]] | ||
| - | [[Category: Seattle structural genomics center for infectious disease]] | ||
[[Category: Ssgcid]] | [[Category: Ssgcid]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 21:05, 25 December 2014
X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus
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