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3c9z

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c9z RCSB], [http://www.ebi.ac.uk/pdbsum/3c9z PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c9z RCSB], [http://www.ebi.ac.uk/pdbsum/3c9z PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
 +
[[http://www.uniprot.org/uniprot/NIGB_SAMNI NIGB_SAMNI]] Non-toxic type 2 RIP which strongly inhibits mammalian protein synthesis but does not affect plant nor bacterial protein synthesis. The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain is a galactose-specific lectin that facilitates the binding of nigrin b to the cell membrane that precedes endocytosis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Sambucus nigra]]
[[Category: Sambucus nigra]]
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[[Category: Guillet, V.]]
+
[[Category: Guillet, V]]
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[[Category: Maveyraud, L.]]
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[[Category: Maveyraud, L]]
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[[Category: Mourey, L.]]
+
[[Category: Mourey, L]]
[[Category: Beta-trefoil]]
[[Category: Beta-trefoil]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]

Revision as of 21:46, 25 December 2014

Sambucus nigra agglutinin II (SNA-II), tetragonal crystal form

3c9z, resolution 1.35Å

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