Sandbox Reserved 966

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==Structure of the C. botulinum neurotoxin serotype A with Zn2+ cofactor bound==
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==Structure of the "Clostridium botulinum" neurotoxin serotype A light chain with Zn2+ cofactor bound==
<StructureSection load='3BON' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='3BON' size='340' side='right' caption='Caption for this structure' scene=''>
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The Clostridium botulinum neurotoxin produced by the bacteria ''Clostridium botulinum'' (and some strains of ''Clostridium butyricium'' and ''Clostridium baratii'') is the most lethal toxin known today. Seven serotypically botulinum neurotoxins (BoNTs) have been found, each of them is categorized into subtypes depending on their amino acid sequence.
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The Clostridium botulinum neurotoxin produced by the bacteria ''Clostridium botulinum'' (and some strains of ''Clostridium butyricium'' and ''Clostridium baratii'') is the most lethal toxin known today. Seven serotypically botulinum neurotoxins (BoNTs) have been found, each of them is categorized into subtypes depending on their amino acid sequence.<ref>PMID: 24975322</ref>
== Function ==
== Function ==

Revision as of 08:52, 30 December 2014

This Sandbox is Reserved from 15/11/2014, through 15/05/2015 for use in the course "Biomolecule" taught by Bruno Kieffer at the Strasbourg University. This reservation includes Sandbox Reserved 951 through Sandbox Reserved 975.
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  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
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More help: Help:Editing

Structure of the "Clostridium botulinum" neurotoxin serotype A light chain with Zn2+ cofactor bound

Caption for this structure

Drag the structure with the mouse to rotate

References

  1. Rossetto O, Pirazzini M, Montecucco C. Botulinum neurotoxins: genetic, structural and mechanistic insights. Nat Rev Microbiol. 2014 Aug;12(8):535-49. doi: 10.1038/nrmicro3295. Epub 2014 Jun, 30. PMID:24975322 doi:http://dx.doi.org/10.1038/nrmicro3295
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