3nss
From Proteopedia
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| - | + | ==The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active sites== | |
| - | + | <StructureSection load='3nss' size='340' side='right' caption='[[3nss]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3nss]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NSS FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3beq|3beq]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nss OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nss RCSB], [http://www.ebi.ac.uk/pdbsum/3nss PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Influenza A virus neuraminidase can be classified into groups 1 and 2 on the basis of its primary structure. The main structural feature of group 1 neuraminidase is an extra cavity in the active site, the 150-cavity. Here we present the crystal structure of neuraminidase from the 2009 pandemic H1N1 influenza strain. In contrast to other characterized N1 neuraminidases, which are all members of group 1, 2009 H1N1 neuraminidase does not have a 150-cavity. | ||
| - | + | The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.,Li Q, Qi J, Zhang W, Vavricka CJ, Shi Y, Wei J, Feng E, Shen J, Chen J, Liu D, He J, Yan J, Liu H, Jiang H, Teng M, Li X, Gao GF Nat Struct Mol Biol. 2010 Oct;17(10):1266-8. Epub 2010 Sep 19. PMID:20852645<ref>PMID:20852645</ref> | |
| - | + | ||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
==See Also== | ==See Also== | ||
*[[Neuraminidase|Neuraminidase]] | *[[Neuraminidase|Neuraminidase]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: I09a0]] | [[Category: I09a0]] | ||
| - | [[Category: Gao, G F | + | [[Category: Gao, G F]] |
| - | [[Category: Li, Q | + | [[Category: Li, Q]] |
| - | [[Category: Qi, J X | + | [[Category: Qi, J X]] |
| - | [[Category: Shi, Y | + | [[Category: Shi, Y]] |
| - | [[Category: Vavricka, C J | + | [[Category: Vavricka, C J]] |
| - | [[Category: Zhang, W | + | [[Category: Zhang, W]] |
[[Category: 6-bladed beta-propeller]] | [[Category: 6-bladed beta-propeller]] | ||
[[Category: Calcium binding]] | [[Category: Calcium binding]] | ||
[[Category: Glycosylation]] | [[Category: Glycosylation]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 21:07, 3 January 2015
The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active sites
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Categories: I09a0 | Gao, G F | Li, Q | Qi, J X | Shi, Y | Vavricka, C J | Zhang, W | 6-bladed beta-propeller | Calcium binding | Glycosylation | Hydrolase
