2g7h
From Proteopedia
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| - | [[Image:2g7h.gif|left|200px]] | + | [[Image:2g7h.gif|left|200px]] |
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| - | '''Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)''' | + | {{Structure |
| + | |PDB= 2g7h |SIZE=350|CAPTION= <scene name='initialview01'>2g7h</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Methylated-DNA--[protein]-cysteine_S-methyltransferase Methylated-DNA--[protein]-cysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.63 2.1.1.63] | ||
| + | |GENE= ogt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]) | ||
| + | }} | ||
| + | |||
| + | '''Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2G7H is a [ | + | 2G7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7H OCA]. |
==Reference== | ==Reference== | ||
| - | Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase., Roberts A, Pelton JG, Wemmer DE, Magn Reson Chem. 2006 Jul;44 Spec No:S71-82. PMID:[http:// | + | Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase., Roberts A, Pelton JG, Wemmer DE, Magn Reson Chem. 2006 Jul;44 Spec No:S71-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16826543 16826543] |
[[Category: Methanocaldococcus jannaschii]] | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: Methylated-DNA--[protein]-cysteine S-methyltransferase]] | [[Category: Methylated-DNA--[protein]-cysteine S-methyltransferase]] | ||
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[[Category: protein structure]] | [[Category: protein structure]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:01:19 2008'' |
Revision as of 15:01, 20 March 2008
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| Gene: | ogt (Methanocaldococcus jannaschii) | ||||||
| Activity: | [protein-cysteine_S-methyltransferase Methylated-DNA--[protein]-cysteine S-methyltransferase], with EC number 2.1.1.63 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of an O6-Methylguanine DNA Methyltransferase from Methanococcus jannaschii (MJ1529)
Overview
The structure of an O6-methylguanine-DNA methyltransferase (MGMT) from the thermophile Methanococcus jannaschii has been determined using multinuclear multidimensional NMR spectroscopy. The structure is similar to homologs from other organisms that have been determined by crystallography, with some variation in the N-terminal domain. The C-terminal domain is more highly conserved in both sequence and structure. Regions of the protein show broadening, reflecting conformational flexibility that is likely related to function.
About this Structure
2G7H is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.
Reference
Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase., Roberts A, Pelton JG, Wemmer DE, Magn Reson Chem. 2006 Jul;44 Spec No:S71-82. PMID:16826543[[Category: Methylated-DNA--[protein]-cysteine S-methyltransferase]]
Page seeded by OCA on Thu Mar 20 17:01:19 2008
