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2h4y

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(New page: 200px<br /><applet load="2h4y" size="350" color="white" frame="true" align="right" spinBox="true" caption="2h4y, resolution 1.90&Aring;" /> '''Crystal structure of...)
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[[Image:2h4y.jpg|left|200px]]<br /><applet load="2h4y" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2h4y.jpg|left|200px]]
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caption="2h4y, resolution 1.90&Aring;" />
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'''Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)'''<br />
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{{Structure
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|PDB= 2h4y |SIZE=350|CAPTION= <scene name='initialview01'>2h4y</scene>, resolution 1.90&Aring;
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|SITE= <scene name='pdbsite=AC1:F3g+Binding+Site+For+Residue+A+501'>AC1</scene>
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|LIGAND= <scene name='pdbligand=F3G:3-[2-(2-BENZYLOXYCARBONYLAMINO-3-METHYL-BUTYRYLAMINO)-PROPIONYLAMINO]-4-OXO-PENTANOIC ACID'>F3G</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36]
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|GENE= CASP1, IL1BC, IL1BCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)'''
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==About this Structure==
==About this Structure==
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2H4Y is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=F3G:'>F3G</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36] Known structural/functional Site: <scene name='pdbsite=AC1:F3g+Binding+Site+For+Residue+A+501'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H4Y OCA].
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2H4Y is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H4Y OCA].
[[Category: Caspase-1]]
[[Category: Caspase-1]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: hydrolase]]
[[Category: hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:30:57 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:12:39 2008''

Revision as of 15:12, 20 March 2008

Image:2h4y.jpg


PDB ID 2h4y

Drag the structure with the mouse to rotate
, resolution 1.90Å
Sites:
Ligands:
Gene: CASP1, IL1BC, IL1BCE (Homo sapiens)
Activity: Caspase-1, with EC number 3.4.22.36
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)


About this Structure

2H4Y is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:12:39 2008

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