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4cfa

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cfa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CFA FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cfa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CFA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WOP:5-[[METHYL-[[(1S)-2-OXIDANYLIDENE-1-PHENYL-2-[(PHENYLMETHYL)AMINO]ETHYL]CARBAMOYL]AMINO]METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC+ACID'>WOP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WOP:5-[[METHYL-[[(1S)-2-OXIDANYLIDENE-1-PHENYL-2-[(PHENYLMETHYL)AMINO]ETHYL]CARBAMOYL]AMINO]METHYL]-1,3-BENZODIOXOLE-4-CARBOXYLIC+ACID'>WOP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ce9|4ce9]], [[4cea|4cea]], [[4ceb|4ceb]], [[4cec|4cec]], [[4ced|4ced]], [[4cee|4cee]], [[4cef|4cef]], [[4ceo|4ceo]], [[4ceq|4ceq]], [[4cer|4cer]], [[4ces|4ces]], [[4cez|4cez]], [[4cf0|4cf0]], [[4cf1|4cf1]], [[4cf2|4cf2]], [[4cf8|4cf8]], [[4cf9|4cf9]], [[4cfb|4cfb]], [[4cfc|4cfc]], [[4cfd|4cfd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ce9|4ce9]], [[4cea|4cea]], [[4ceb|4ceb]], [[4cec|4cec]], [[4ced|4ced]], [[4cee|4cee]], [[4cef|4cef]], [[4ceo|4ceo]], [[4ceq|4ceq]], [[4cer|4cer]], [[4ces|4ces]], [[4cez|4cez]], [[4cf0|4cf0]], [[4cf1|4cf1]], [[4cf2|4cf2]], [[4cf8|4cf8]], [[4cf9|4cf9]], [[4cfb|4cfb]], [[4cfc|4cfc]], [[4cfd|4cfd]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cfa RCSB], [http://www.ebi.ac.uk/pdbsum/4cfa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cfa RCSB], [http://www.ebi.ac.uk/pdbsum/4cfa PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 9hiv1]]
 
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
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[[Category: Peat, T S.]]
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[[Category: Peat, T S]]
[[Category: Structure based drug design]]
[[Category: Structure based drug design]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 14:28, 4 January 2015

Interrogating HIV integrase for compounds that bind- a SAMPL challenge

4cfa, resolution 2.05Å

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