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2hvp

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[[Image:2hvp.gif|left|200px]]<br /><applet load="2hvp" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2hvp.gif|left|200px]]
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caption="2hvp, resolution 3.0&Aring;" />
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'''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''<br />
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{{Structure
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|PDB= 2hvp |SIZE=350|CAPTION= <scene name='initialview01'>2hvp</scene>, resolution 3.0&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2HVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVP OCA].
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2HVP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVP OCA].
==Reference==
==Reference==
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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2645523 2645523]
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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2645523 2645523]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase(acid proteinase)]]
[[Category: hydrolase(acid proteinase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:22:10 2008''

Revision as of 15:22, 20 March 2008


PDB ID 2hvp

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, resolution 3.0Å
Coordinates: save as pdb, mmCIF, xml



THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1


Overview

The crystal structure of the protease of the human immunodeficiency virus type (HIV-1), which releases structural proteins and enzymes from viral polyprotein products, has been determined to 3 A resolution. Large regions of the protease dimer, including the active site, have structural homology to the family of microbial aspartyl proteases. The structure suggests a mechanism for the autoproteolytic release of protease and a role in the control of virus maturation.

About this Structure

2HVP is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:2645523

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