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1mui

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mui]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MUI FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mui]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MUI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mui OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mui RCSB], [http://www.ebi.ac.uk/pdbsum/1mui PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mui OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mui RCSB], [http://www.ebi.ac.uk/pdbsum/1mui PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Bussiere, D.]]
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[[Category: Bussiere, D]]
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[[Category: Helfrich, R.]]
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[[Category: Helfrich, R]]
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[[Category: Jakob, C.]]
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[[Category: Jakob, C]]
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[[Category: Kao, J.]]
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[[Category: Kao, J]]
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[[Category: Kempf, D.]]
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[[Category: Kempf, D]]
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[[Category: Norbeck, D W.]]
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[[Category: Norbeck, D W]]
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[[Category: Park, C.]]
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[[Category: Park, C]]
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[[Category: Qin, W.]]
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[[Category: Qin, W]]
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[[Category: Sham, H L.]]
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[[Category: Sham, H L]]
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[[Category: Simmer, R L.]]
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[[Category: Simmer, R L]]
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[[Category: Stewart, K D.]]
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[[Category: Stewart, K D]]
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[[Category: Stoll, V.]]
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[[Category: Stoll, V]]
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[[Category: Walter, K.]]
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[[Category: Walter, K]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 16:28, 5 January 2015

Crystal structure of HIV-1 protease complexed with Lopinavir.

1mui, resolution 2.80Å

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