1mif

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mif]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mif]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mif OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mif RCSB], [http://www.ebi.ac.uk/pdbsum/1mif PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mif OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mif RCSB], [http://www.ebi.ac.uk/pdbsum/1mif PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/MIF_HUMAN MIF_HUMAN]] Genetic variations in MIF are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:[http://omim.org/entry/604302 604302]]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
[[http://www.uniprot.org/uniprot/MIF_HUMAN MIF_HUMAN]] Genetic variations in MIF are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:[http://omim.org/entry/604302 604302]]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lolis, E.]]
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[[Category: Lolis, E]]
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[[Category: Sun, H W.]]
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[[Category: Sun, H W]]
[[Category: Cytokine]]
[[Category: Cytokine]]
[[Category: Glutathione binding protein]]
[[Category: Glutathione binding protein]]
[[Category: Hormone]]
[[Category: Hormone]]

Revision as of 16:55, 5 January 2015

MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)

1mif, resolution 2.60Å

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