2i9f

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[[Image:2i9f.jpg|left|200px]]<br /><applet load="2i9f" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2i9f.jpg|left|200px]]
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caption="2i9f, resolution 2.00&Aring;" />
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'''Structure of the equine arterivirus nucleocapsid protein'''<br />
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{{Structure
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|PDB= 2i9f |SIZE=350|CAPTION= <scene name='initialview01'>2i9f</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY=
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|GENE= ORF7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11047 Equine arteritis virus])
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}}
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'''Structure of the equine arterivirus nucleocapsid protein'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2I9F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equine_arteritis_virus Equine arteritis virus] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=DTT:'>DTT</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9F OCA].
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2I9F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equine_arteritis_virus Equine arteritis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I9F OCA].
==Reference==
==Reference==
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Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement., Deshpande A, Wang S, Walsh MA, Dokland T, Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17452783 17452783]
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Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement., Deshpande A, Wang S, Walsh MA, Dokland T, Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17452783 17452783]
[[Category: Equine arteritis virus]]
[[Category: Equine arteritis virus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: virus]]
[[Category: virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:50:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:26:49 2008''

Revision as of 15:26, 20 March 2008

Image:2i9f.jpg


PDB ID 2i9f

Drag the structure with the mouse to rotate
, resolution 2.00Å
Ligands: , , and
Gene: ORF7 (Equine arteritis virus)
Coordinates: save as pdb, mmCIF, xml



Structure of the equine arterivirus nucleocapsid protein


Overview

Equine arteritis virus (EAV) is an enveloped positive-sense RNA virus belonging to the Arteriviridae family, which also includes the porcine pathogen PRRSV and is genetically and structurally related to the coronaviruses. EAV is an important equine pathogen that has caused significant economic losses to the horse-breeding industry and has been difficult to control. The EAV virion consists of a genome-containing nucleocapsid core made of nucleocapsid (N) protein surrounded by a lipid envelope containing several membrane proteins. Here, the crystal structure of the capsid-forming domain of the EAV N protein is presented at 2.0 A resolution. The dimeric N-protein structure is similar to the previously determined structure of the N protein from PRRSV, with most differences localized to the terminal helices and flexible loops. The N protein is organized as dimers of dimers in the crystal, which may reflect the arrangement of the protein in the viral nucleocapsid.

About this Structure

2I9F is a Single protein structure of sequence from Equine arteritis virus. Full crystallographic information is available from OCA.

Reference

Structure of the equine arteritis virus nucleocapsid protein reveals a dimer-dimer arrangement., Deshpande A, Wang S, Walsh MA, Dokland T, Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):581-6. Epub 2007, Apr 21. PMID:17452783

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