2ic9
From Proteopedia
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| - | [[Image:2ic9.jpg|left|200px]] | + | [[Image:2ic9.jpg|left|200px]] |
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| - | '''The Coiled-coil Domain (residues 1-93) Structure of the Sin Nombre Virus Nucleocapsid Protein''' | + | {{Structure |
| + | |PDB= 2ic9 |SIZE=350|CAPTION= <scene name='initialview01'>2ic9</scene>, resolution 2.000Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= nucleocapsid protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=37705 Sin Nombre virus]) | ||
| + | }} | ||
| + | |||
| + | '''The Coiled-coil Domain (residues 1-93) Structure of the Sin Nombre Virus Nucleocapsid Protein''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2IC9 is a [ | + | 2IC9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sin_nombre_virus Sin nombre virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IC9 OCA]. |
==Reference== | ==Reference== | ||
| - | The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:[http:// | + | The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17222867 17222867] |
[[Category: Sin nombre virus]] | [[Category: Sin nombre virus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: nucleocapsid protein]] | [[Category: nucleocapsid protein]] | ||
[[Category: sin nombre virus]] | [[Category: sin nombre virus]] | ||
| - | [[Category: ssrna negative-strand | + | [[Category: ssrna negative-strand viruse]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:27:48 2008'' |
Revision as of 15:27, 20 March 2008
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| , resolution 2.000Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | nucleocapsid protein (Sin Nombre virus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
The Coiled-coil Domain (residues 1-93) Structure of the Sin Nombre Virus Nucleocapsid Protein
Overview
Hantaviruses can cause hemorrhagic fever with a renal syndrome and hantavirus pulmonary syndrome when transmitted to humans. The nucleocapsid protein of hantaviruses encapsidates viral genomic RNA and associates with transcription and replication complexes. Both the amino and carboxy termini of the nucleocapsid protein had been predicted to form trimers prior to the formation of the ribonucleoprotein. Crystal structures of amino-terminal fragments of the nucleocapsid protein showed the formation of intramolecular antiparallel coiled coils, but not intermolecular trimers. Thus, the amino-terminal part of the nucleocapsid protein is probably insufficient to initiate the trimerization of the full-length molecule.
About this Structure
2IC9 is a Single protein structure of sequence from Sin nombre virus. Full crystallographic information is available from OCA.
Reference
The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:17222867
Page seeded by OCA on Thu Mar 20 17:27:48 2008
