This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1w6h
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W6H FirstGlance]. <br> | <table><tr><td colspan='2'>[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W6H FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TIT:N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE'>TIT</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TIT:N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE'>TIT</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j8j|1j8j]], [[1lee|1lee]], [[1lf2|1lf2]], [[1lf3|1lf3]], [[1lf4|1lf4]], [[1m43|1m43]], [[1me6|1me6]], [[1pfz|1pfz]], [[1sme|1sme]], [[1w6i|1w6i]], [[1xdh|1xdh]], [[1xe5|1xe5]], [[1xe6|1xe6]], [[2bju|2bju]], [[2bl3|2bl3]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j8j|1j8j]], [[1lee|1lee]], [[1lf2|1lf2]], [[1lf3|1lf3]], [[1lf4|1lf4]], [[1m43|1m43]], [[1me6|1me6]], [[1pfz|1pfz]], [[1sme|1sme]], [[1w6i|1w6i]], [[1xdh|1xdh]], [[1xe5|1xe5]], [[1xe6|1xe6]], [[2bju|2bju]], [[2bl3|2bl3]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w6h RCSB], [http://www.ebi.ac.uk/pdbsum/1w6h PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w6h RCSB], [http://www.ebi.ac.uk/pdbsum/1w6h PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 25: | ||
[[Category: Plasmepsin II]] | [[Category: Plasmepsin II]] | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: Johansson, P O | + | [[Category: Johansson, P O]] |
| - | [[Category: Kvarnstroem, I | + | [[Category: Kvarnstroem, I]] |
| - | [[Category: Lindberg, J | + | [[Category: Lindberg, J]] |
| - | [[Category: Rosenquist, A | + | [[Category: Rosenquist, A]] |
| - | [[Category: Samuelsson, B | + | [[Category: Samuelsson, B]] |
| - | [[Category: Unge, T | + | [[Category: Unge, T]] |
| - | [[Category: Vrang, L | + | [[Category: Vrang, L]] |
[[Category: Aspartic protease]] | [[Category: Aspartic protease]] | ||
[[Category: Drug]] | [[Category: Drug]] | ||
Revision as of 12:43, 6 January 2015
NOVEL PLASMEPSIN II-INHIBITOR COMPLEX
| |||||||||||
