1v9u

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1v9u]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_rhinovirus_a2 Human rhinovirus a2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V9U FirstGlance]. <br>
<table><tr><td colspan='2'>[[1v9u]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_rhinovirus_a2 Human rhinovirus a2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V9U FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fpn|1fpn]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fpn|1fpn]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v9u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v9u RCSB], [http://www.ebi.ac.uk/pdbsum/1v9u PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v9u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v9u RCSB], [http://www.ebi.ac.uk/pdbsum/1v9u PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/VLDLR_HUMAN VLDLR_HUMAN]] Defects in VLDLR are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 1 (CMARQ1) [MIM:[http://omim.org/entry/224050 224050]]; also known as dysequilibrium syndrome (DES) or non-progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures.<ref>PMID:16080122</ref>
[[http://www.uniprot.org/uniprot/VLDLR_HUMAN VLDLR_HUMAN]] Defects in VLDLR are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 1 (CMARQ1) [MIM:[http://omim.org/entry/224050 224050]]; also known as dysequilibrium syndrome (DES) or non-progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures.<ref>PMID:16080122</ref>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human rhinovirus a2]]
[[Category: Human rhinovirus a2]]
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[[Category: Blaas, D.]]
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[[Category: Blaas, D]]
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[[Category: Fita, I.]]
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[[Category: Fita, I]]
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[[Category: Moser, R.]]
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[[Category: Moser, R]]
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[[Category: Reithmayer, M.]]
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[[Category: Reithmayer, M]]
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[[Category: Verdaguer, N.]]
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[[Category: Verdaguer, N]]
[[Category: Human rhinovirus]]
[[Category: Human rhinovirus]]
[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]

Revision as of 13:24, 6 January 2015

Human Rhinovirus 2 bound to a fragment of its cellular receptor protein

1v9u, resolution 3.60Å

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