Sandbox Reserved 966

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== Therapeutic applications ==
== Therapeutic applications ==
In the late 1960s, a Edward Schantz and a San Francisco opthalmologist, Alan Scott, start to work on the using of the botulinum toxin in therapeutic process.
In the late 1960s, a Edward Schantz and a San Francisco opthalmologist, Alan Scott, start to work on the using of the botulinum toxin in therapeutic process.
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First, they try to treat strabismus and in the late 1970s the neurotoxin is used in many therapeutic applications.
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First, they try to treat strabismus and in the late 1970s the neurotoxin is used in many therapeutic applications. REFERENCE ?
=== hyperhidrosis and CHARGE syndrome ===
=== hyperhidrosis and CHARGE syndrome ===
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We can now treat excessive sweating with botulinium toxin <ref>http://rms.medhyg.ch/numero-200-page-870.htm</ref> thanks to his action on the receptors of the parasympathetic network. Excessive dribbling can be treated in the same way.
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We can now treat excessive sweating with botulinium toxin <ref>http://rms.medhyg.ch/numero-200-page-870.htm</ref> thanks to its action on the receptors of the parasympathetic network. Excessive dribbling can be treated in the same way.
=== Cosmetic ===
=== Cosmetic ===
Non-lethal amount of botulinum toxin can be injected localy to paralyse targeted muscles and reduce wrinkles temporaly<ref>http://rms.medhyg.ch/numero-200-page-870.htm</ref> (5 to 6 months).
Non-lethal amount of botulinum toxin can be injected localy to paralyse targeted muscles and reduce wrinkles temporaly<ref>http://rms.medhyg.ch/numero-200-page-870.htm</ref> (5 to 6 months).

Revision as of 07:23, 8 January 2015

This Sandbox is Reserved from 15/11/2014, through 15/05/2015 for use in the course "Biomolecule" taught by Bruno Kieffer at the Strasbourg University. This reservation includes Sandbox Reserved 951 through Sandbox Reserved 975.
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Structure of the "Clostridium botulinum" neurotoxin serotype A light chain with Zn2+ cofactor bound

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