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2ahr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ahr]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AHR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ahr]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AHR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yqg|1yqg]], [[2ag8|2ag8]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yqg|1yqg]], [[2ag8|2ag8]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrroline-5-carboxylate_reductase Pyrroline-5-carboxylate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.2 1.5.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrroline-5-carboxylate_reductase Pyrroline-5-carboxylate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.2 1.5.1.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ahr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ahr RCSB], [http://www.ebi.ac.uk/pdbsum/2ahr PDBsum], [http://www.topsan.org/Proteins/MCSG/2ahr TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ahr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ahr RCSB], [http://www.ebi.ac.uk/pdbsum/2ahr PDBsum], [http://www.topsan.org/Proteins/MCSG/2ahr TOPSAN]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Pyrroline-5-carboxylate reductase]]
[[Category: Pyrroline-5-carboxylate reductase]]
[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
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[[Category: Holzle, D.]]
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[[Category: Holzle, D]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Lezondra, L.]]
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[[Category: Lezondra, L]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Nocek, B.]]
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[[Category: Nocek, B]]
[[Category: 1-pyrroline-5-carboxylate reductase]]
[[Category: 1-pyrroline-5-carboxylate reductase]]
[[Category: Doain swapping]]
[[Category: Doain swapping]]
[[Category: Human pathogen]]
[[Category: Human pathogen]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Proline biosynthesis]]
[[Category: Proline biosynthesis]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrroline reductase]]
[[Category: Pyrroline reductase]]
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[[Category: Pyrroline-5-carboxylate reductase]]
 
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Streptococcus pyogene]]
[[Category: Streptococcus pyogene]]
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[[Category: Structural genomic]]
 

Revision as of 09:47, 8 January 2015

Crystal Structures of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus pyogenes

2ahr, resolution 2.15Å

Drag the structure with the mouse to rotate

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