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1yvf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1yvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YVF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1yvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YVF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH7:(2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC+ACID'>PH7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH7:(2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC+ACID'>PH7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yvf RCSB], [http://www.ebi.ac.uk/pdbsum/1yvf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yvf RCSB], [http://www.ebi.ac.uk/pdbsum/1yvf PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
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[[Category: Anstadt, R A.]]
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[[Category: Anstadt, R A]]
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[[Category: Finzel, B C.]]
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[[Category: Finzel, B C]]
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[[Category: Greene, M L.]]
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[[Category: Greene, M L]]
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[[Category: Gross, R J.]]
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[[Category: Gross, R J]]
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[[Category: Harris, M S.]]
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[[Category: Harris, M S]]
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[[Category: Kilkuskie, R E.]]
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[[Category: Kilkuskie, R E]]
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[[Category: Kopta, L A.]]
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[[Category: Kopta, L A]]
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[[Category: Mitchell, M A.]]
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[[Category: Mitchell, M A]]
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[[Category: Nugent, R A.]]
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[[Category: Nugent, R A]]
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[[Category: Pfefferkorn, J A.]]
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[[Category: Pfefferkorn, J A]]
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[[Category: Schwende, F J.]]
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[[Category: Schwende, F J]]
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[[Category: Shelly, J A.]]
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[[Category: Shelly, J A]]
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[[Category: Wells, P A.]]
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[[Category: Wells, P A]]
[[Category: Finger]]
[[Category: Finger]]
[[Category: Hcv]]
[[Category: Hcv]]

Revision as of 10:23, 8 January 2015

Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145

1yvf, resolution 2.50Å

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