4x01
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==S. pombe Ctp1 tetramerization domain== |
| - | + | <StructureSection load='4x01' size='340' side='right' caption='[[4x01]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x01]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X01 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x01 RCSB], [http://www.ebi.ac.uk/pdbsum/4x01 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[Category: Andres, S | + | [[http://www.uniprot.org/uniprot/COM1_SCHPO COM1_SCHPO]] Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sites and ensuring both resection and intrachromosomal association of the broken ends. Required for the formation of RPA-coated single strand DNA adjacent to the DSBs where it functions together with the MRN complex in 5'- 3' resection. Required for the repair of programmed meiotic DSBs. Involved also in an rhp51 recombinase-dependent recombinational repair pathway.<ref>PMID:16303567</ref> <ref>PMID:17936710</ref> <ref>PMID:18378696</ref> <ref>PMID:19139281</ref> |
| - | [[Category: Williams, R | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Andres, S N]] | ||
| + | [[Category: Williams, R S]] | ||
| + | [[Category: Dna binding]] | ||
| + | [[Category: Dna double-strand break repair]] | ||
| + | [[Category: Four-helix bundle]] | ||
| + | [[Category: Homologous recombination]] | ||
Revision as of 13:49, 14 January 2015
S. pombe Ctp1 tetramerization domain
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