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2jc0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jc0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JC0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jc0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JC0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=699:(2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC+ACID'>699</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=699:(2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC+ACID'>699</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i1r|2i1r]], [[2jc1|2jc1]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i1r|2i1r]], [[2jc1|2jc1]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2jc0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2jc0 PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
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[[Category: Singh, O M.]]
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[[Category: Singh, O M]]
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[[Category: Skarzynski, T.]]
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[[Category: Skarzynski, T]]
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[[Category: Wonacott, A.]]
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[[Category: Wonacott, A]]
[[Category: Hepatitis]]
[[Category: Hepatitis]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Polymerase]]
[[Category: Polymerase]]

Revision as of 14:40, 19 January 2015

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264

2jc0, resolution 2.20Å

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