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2vqt

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vqt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vqt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15A:(2Z,3R,4S,5R,6R)-2-[(2-AMINOETHYL)IMINO]-6-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL'>15A</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15A:(2Z,3R,4S,5R,6R)-2-[(2-AMINOETHYL)IMINO]-6-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL'>15A</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vot|2vot]], [[2vl4|2vl4]], [[2vqu|2vqu]], [[2vo5|2vo5]], [[2je8|2je8]], [[2vr4|2vr4]], [[2vjx|2vjx]], [[2vmf|2vmf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vot|2vot]], [[2vl4|2vl4]], [[2vqu|2vqu]], [[2vo5|2vo5]], [[2je8|2je8]], [[2vr4|2vr4]], [[2vjx|2vjx]], [[2vmf|2vmf]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-mannosidase Beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.25 3.2.1.25] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-mannosidase Beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.25 3.2.1.25] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqt RCSB], [http://www.ebi.ac.uk/pdbsum/2vqt PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqt RCSB], [http://www.ebi.ac.uk/pdbsum/2vqt PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bacteroides thetaiotaomicron]]
[[Category: Bacteroides thetaiotaomicron]]
[[Category: Beta-mannosidase]]
[[Category: Beta-mannosidase]]
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[[Category: Bleriot, Y.]]
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[[Category: Bleriot, Y]]
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[[Category: Davies, G J.]]
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[[Category: Davies, G J]]
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[[Category: Dumon, C.]]
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[[Category: Dumon, C]]
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[[Category: Gilbert, H J.]]
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[[Category: Gilbert, H J]]
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[[Category: Gratien, J.]]
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[[Category: Gratien, J]]
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[[Category: Heck, M P.]]
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[[Category: Heck, M P]]
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[[Category: Moreland, C.]]
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[[Category: Moreland, C]]
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[[Category: Offen, W A.]]
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[[Category: Offen, W A]]
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[[Category: Smith, N L.]]
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[[Category: Smith, N L]]
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[[Category: Stick, R V.]]
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[[Category: Stick, R V]]
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[[Category: Tailford, L E.]]
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[[Category: Tailford, L E]]
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[[Category: Vasella, A.]]
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[[Category: Vasella, A]]
[[Category: Glycoside hydrolase]]
[[Category: Glycoside hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 15:40, 19 January 2015

STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES

2vqt, resolution 2.10Å

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