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2o23
From Proteopedia
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| - | [[Image:2o23.jpg|left|200px]] | + | [[Image:2o23.jpg|left|200px]] |
| - | + | ||
| - | '''The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A''' | + | {{Structure |
| + | |PDB= 2o23 |SIZE=350|CAPTION= <scene name='initialview01'>2o23</scene>, resolution 1.20Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/3-hydroxy-2-methylbutyryl-CoA_dehydrogenase 3-hydroxy-2-methylbutyryl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.178 1.1.1.178] | ||
| + | |GENE= HADH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A''' | ||
| + | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2O23 is a [ | + | 2O23 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O23 OCA]. |
[[Category: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase]] | [[Category: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: schad]] | [[Category: schad]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
[[Category: type ii hadh]] | [[Category: type ii hadh]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:54:06 2008'' |
Revision as of 15:54, 20 March 2008
| |||||||
| , resolution 1.20Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Gene: | HADH2 (Homo sapiens) | ||||||
| Activity: | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, with EC number 1.1.1.178 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
Disease
Known disease associated with this structure: 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency OMIM:[300256]
About this Structure
2O23 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:54:06 2008
Categories: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase | Homo sapiens | Single protein | Arrowsmith, C. | Debreczeni, J. | Delft, F Von. | Edwards, A. | Kavanagh, K L. | Oppermann, U. | SGC, Structural Genomics Consortium. | Scholer, K. | Shafqat, N. | Sundstrom, M. | Weigelt, J. | Zschocke, J. | GOL | NAD | 2-methyl-3-hydroxybutyryl-coa dehydrogenase | Erab | Hsd17b10 | Mhbd | Schad | Sgc | Structural genomic | Structural genomics consortium | Type ii hadh
