2o4h

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[[Image:2o4h.jpg|left|200px]]<br /><applet load="2o4h" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2o4h.jpg|left|200px]]
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caption="2o4h, resolution 2.70&Aring;" />
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'''Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate)'''<br />
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{{Structure
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|PDB= 2o4h |SIZE=350|CAPTION= <scene name='initialview01'>2o4h</scene>, resolution 2.70&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=AS9:N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID'>AS9</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartoacylase Aspartoacylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.15 3.5.1.15]
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|GENE= ASPA, ACY2, ASP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate)'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2O4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=AS9:'>AS9</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aspartoacylase Aspartoacylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.15 3.5.1.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4H OCA].
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2O4H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4H OCA].
[[Category: Aspartoacylase]]
[[Category: Aspartoacylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: zinc-dependent hydrolase]]
[[Category: zinc-dependent hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:14:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:54:57 2008''

Revision as of 15:54, 20 March 2008


PDB ID 2o4h

Drag the structure with the mouse to rotate
, resolution 2.70Å
Ligands: and
Gene: ASPA, ACY2, ASP (Homo sapiens)
Activity: Aspartoacylase, with EC number 3.5.1.15
Coordinates: save as pdb, mmCIF, xml



Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate)


Disease

Known diseases associated with this structure: Canavan disease OMIM:[608034]

About this Structure

2O4H is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:54:57 2008

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