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2k40
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2k40]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K40 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2k40]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K40 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K40 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HESX1, HANF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HESX1, HANF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k40 RCSB], [http://www.ebi.ac.uk/pdbsum/2k40 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k40 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k40 RCSB], [http://www.ebi.ac.uk/pdbsum/2k40 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/HESX1_HUMAN HESX1_HUMAN]] Hypothyroidism due to deficient transcription factors involved in pituitary development or function;Combined pituitary hormone deficiencies, genetic forms;Pituitary stalk interruption syndrome;Septo-optic dysplasia;Kallmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:9620767</ref> <ref>PMID:11136712</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:11136712</ref> <ref>PMID:17148560</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:11136712</ref> <ref>PMID:14561704</ref> | [[http://www.uniprot.org/uniprot/HESX1_HUMAN HESX1_HUMAN]] Hypothyroidism due to deficient transcription factors involved in pituitary development or function;Combined pituitary hormone deficiencies, genetic forms;Pituitary stalk interruption syndrome;Septo-optic dysplasia;Kallmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:9620767</ref> <ref>PMID:11136712</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:11136712</ref> <ref>PMID:17148560</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:11136712</ref> <ref>PMID:14561704</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Asensio, J | + | [[Category: Asensio, J]] |
| - | [[Category: Bastida, A | + | [[Category: Bastida, A]] |
| - | [[Category: Gonzalez, C | + | [[Category: Gonzalez, C]] |
| - | [[Category: Torrado, M | + | [[Category: Torrado, M]] |
[[Category: Developmental protein]] | [[Category: Developmental protein]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
Revision as of 17:26, 19 January 2015
NMR structure of HESX-1 homeodomain double mutant R31L/E42L
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