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2x38
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x38]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2wxe 2wxe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X38 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2x38]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2wxe 2wxe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X38 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IC8:2-[(6-AMINO-9H-PURIN-9-YL)METHYL]-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE'>IC8</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IC8:2-[(6-AMINO-9H-PURIN-9-YL)METHYL]-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE'>IC8</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x38 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x38 RCSB], [http://www.ebi.ac.uk/pdbsum/2x38 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x38 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x38 RCSB], [http://www.ebi.ac.uk/pdbsum/2x38 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 34: | Line 34: | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
| - | [[Category: Berndt, A | + | [[Category: Berndt, A]] |
| - | [[Category: Gaillard, P | + | [[Category: Gaillard, P]] |
| - | [[Category: Gorrec, F | + | [[Category: Gorrec, F]] |
| - | [[Category: Hon, W C | + | [[Category: Hon, W C]] |
| - | [[Category: Houseman, B T | + | [[Category: Houseman, B T]] |
| - | [[Category: Lee, D D | + | [[Category: Lee, D D]] |
| - | [[Category: Liu, Y | + | [[Category: Liu, Y]] |
| - | [[Category: Miller, S | + | [[Category: Miller, S]] |
| - | [[Category: Pacold, J I | + | [[Category: Pacold, J I]] |
| - | [[Category: Rommel, C | + | [[Category: Rommel, C]] |
| - | [[Category: Ruckle, T | + | [[Category: Ruckle, T]] |
| - | [[Category: Schwarz, M K | + | [[Category: Schwarz, M K]] |
| - | [[Category: Shaw, J P | + | [[Category: Shaw, J P]] |
| - | [[Category: Shokat, K M | + | [[Category: Shokat, K M]] |
| - | [[Category: Williams, O | + | [[Category: Williams, O]] |
| - | [[Category: Williams, R L | + | [[Category: Williams, R L]] |
[[Category: Cancer]] | [[Category: Cancer]] | ||
[[Category: Isoform-specific inhibitor]] | [[Category: Isoform-specific inhibitor]] | ||
[[Category: Phosphoinositide 3-kinase]] | [[Category: Phosphoinositide 3-kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 09:22, 20 January 2015
THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH IC87114.
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Categories: Mus musculus | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Berndt, A | Gaillard, P | Gorrec, F | Hon, W C | Houseman, B T | Lee, D D | Liu, Y | Miller, S | Pacold, J I | Rommel, C | Ruckle, T | Schwarz, M K | Shaw, J P | Shokat, K M | Williams, O | Williams, R L | Cancer | Isoform-specific inhibitor | Phosphoinositide 3-kinase | Transferase
