This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2wcx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WCX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WCX FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=VGC:6-CYCLOHEXYL-4-METHYL-5-PHENYL-4H-THIENO[3,2-B]PYRROLE-2-CARBOXYLIC+ACID'>VGC</scene><br>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=VGC:6-CYCLOHEXYL-4-METHYL-5-PHENYL-4H-THIENO[3,2-B]PYRROLE-2-CARBOXYLIC+ACID'>VGC</scene></td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nhu|1nhu]], [[2i1r|2i1r]], [[1jxp|1jxp]], [[2jc1|2jc1]], [[1gx6|1gx6]], [[1a1q|1a1q]], [[1c2p|1c2p]], [[1cu1|1cu1]], [[1ns3|1ns3]], [[2jc0|2jc0]], [[2ax1|2ax1]], [[1nhv|1nhv]], [[1csj|1csj]], [[2brl|2brl]], [[2brk|2brk]], [[1gx5|1gx5]], [[2ax0|2ax0]], [[2awz|2awz]], [[1quv|1quv]], [[1os5|1os5]]</td></tr>
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nhu|1nhu]], [[2i1r|2i1r]], [[1jxp|1jxp]], [[2jc1|2jc1]], [[1gx6|1gx6]], [[1a1q|1a1q]], [[1c2p|1c2p]], [[1cu1|1cu1]], [[1ns3|1ns3]], [[2jc0|2jc0]], [[2ax1|2ax1]], [[1nhv|1nhv]], [[1csj|1csj]], [[2brl|2brl]], [[2brk|2brk]], [[1gx5|1gx5]], [[2ax0|2ax0]], [[2awz|2awz]], [[1quv|1quv]], [[1os5|1os5]]</td></tr>
-
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wcx RCSB], [http://www.ebi.ac.uk/pdbsum/2wcx PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wcx RCSB], [http://www.ebi.ac.uk/pdbsum/2wcx PDBsum]</span></td></tr>
-
<table>
+
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 25:
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
-
[[Category: Marco, S Di.]]
+
[[Category: Marco, S Di]]
[[Category: Allosteric inhibitor]]
[[Category: Allosteric inhibitor]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
Line 32: Line 32:
[[Category: Hcv]]
[[Category: Hcv]]
[[Category: Helicase]]
[[Category: Helicase]]
-
[[Category: Hepatitis c virus]]
 
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Membrane]]

Revision as of 10:48, 20 January 2015

CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS

2wcx, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wcx"
Personal tools