This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4cbl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Pestivirus NS3 helicase==
-
 
+
<StructureSection load='4cbl' size='340' side='right' caption='[[4cbl]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
-
The entry 4cbl is ON HOLD until Paper Publication
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4cbl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CBL FirstGlance]. <br>
-
Authors: Tortorici, M.A., Duquerroy, S., Vonrhein, C., Perez, J., Lamp, B., GirardBlanc, C., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cbg|4cbg]], [[4cbh|4cbh]], [[4cbi|4cbi]], [[4cbm|4cbm]]</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cbl RCSB], [http://www.ebi.ac.uk/pdbsum/4cbl PDBsum]</span></td></tr>
-
Description: Pestivirus NS3 helicase
+
</table>
-
[[Category: Unreleased Structures]]
+
== Function ==
-
[[Category: Lamp, B]]
+
[[http://www.uniprot.org/uniprot/POLG_CSFVA POLG_CSFVA]] E(rns), E1 and E2 are responsible of cell attachment and subsequent fusion of viral and cellular membrane. P7 forms a leader sequence to properly orient NS2 in the membrane. Uncleaved NS2-3 is required for production of infectious virus. NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus.[PROSITE-ProRule:PRU01029] NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase. NS4A is a cofactor for the NS3 protease activity. RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome.[PROSITE-ProRule:PRU00539]
-
[[Category: Vachette, P]]
+
__TOC__
-
[[Category: Rumenapf, T]]
+
</StructureSection>
[[Category: Bricogne, G]]
[[Category: Bricogne, G]]
 +
[[Category: Duquerroy, S]]
 +
[[Category: Kwok, J]]
 +
[[Category: Lamp, B]]
[[Category: Perez, J]]
[[Category: Perez, J]]
 +
[[Category: Rey, F A]]
 +
[[Category: Rumenapf, T]]
 +
[[Category: Tortorici, M A]]
 +
[[Category: Vachette, P]]
[[Category: Vonrhein, C]]
[[Category: Vonrhein, C]]
-
[[Category: Duquerroy, S]]
+
[[Category: Flaviviridae ns3]]
-
[[Category: Tortorici, M.A]]
+
[[Category: Hydrolase]]
-
[[Category: Rey, F.A]]
+
[[Category: Pestivirus]]
-
[[Category: Girardblanc, C]]
+
[[Category: Sax]]
 +
[[Category: Sf2 helicase]]

Revision as of 16:55, 21 January 2015

Pestivirus NS3 helicase

4cbl, resolution 3.05Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cbl"
Personal tools