2phr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2phr.jpg|left|200px]]<br /><applet load="2phr" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:2phr.jpg|left|200px]]
-
caption="2phr, resolution 1.90&Aring;" />
+
 
-
'''Pterocarpus angolensis lectin (PAL) in complex with Man-7D1'''<br />
+
{{Structure
 +
|PDB= 2phr |SIZE=350|CAPTION= <scene name='initialview01'>2phr</scene>, resolution 1.90&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''Pterocarpus angolensis lectin (PAL) in complex with Man-7D1'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
2PHR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pterocarpus_angolensis Pterocarpus angolensis] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHR OCA].
+
2PHR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pterocarpus_angolensis Pterocarpus angolensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHR OCA].
==Reference==
==Reference==
-
How a plant lectin recognizes high mannose oligosaccharides., Garcia-Pino A, Buts L, Wyns L, Imberty A, Loris R, Plant Physiol. 2007 Aug;144(4):1733-41. Epub 2007 Jun 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17556509 17556509]
+
How a plant lectin recognizes high mannose oligosaccharides., Garcia-Pino A, Buts L, Wyns L, Imberty A, Loris R, Plant Physiol. 2007 Aug;144(4):1733-41. Epub 2007 Jun 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17556509 17556509]
[[Category: Pterocarpus angolensis]]
[[Category: Pterocarpus angolensis]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 24: Line 33:
[[Category: lectin]]
[[Category: lectin]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:29:32 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:13:08 2008''

Revision as of 16:13, 20 March 2008

Image:2phr.jpg


PDB ID 2phr

Drag the structure with the mouse to rotate
, resolution 1.90Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



Pterocarpus angolensis lectin (PAL) in complex with Man-7D1


Overview

The crystal structure of Pterocarpus angolensis seed lectin is presented in complex with a series of high mannose (Man) oligosaccharides ranging from Man-5 to Man-9. Despite that several of the nine Man residues of Man-9 have the potential to bind in the monosaccharide-binding site, all oligomannoses are bound in the same unique way, employing the tetrasaccharide sequence Manalpha(1-2)Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-. Isothermal titration calorimetry titration experiments using Man-5, Man-9, and the Man-9-containing glycoprotein soybean (Glycine max) agglutinin as ligands confirm the monovalence of Man-9 and show a 4-times higher affinity for Man-9 when it is presented to P. angolensis seed lectin in a glycoprotein context.

About this Structure

2PHR is a Single protein structure of sequence from Pterocarpus angolensis. Full crystallographic information is available from OCA.

Reference

How a plant lectin recognizes high mannose oligosaccharides., Garcia-Pino A, Buts L, Wyns L, Imberty A, Loris R, Plant Physiol. 2007 Aug;144(4):1733-41. Epub 2007 Jun 7. PMID:17556509

Page seeded by OCA on Thu Mar 20 18:13:08 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2phr"
Personal tools