2pit

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[[Image:2pit.jpg|left|200px]]<br /><applet load="2pit" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2pit.jpg|left|200px]]
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caption="2pit, resolution 1.76&Aring;" />
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'''Androgen receptor LBD with small molecule'''<br />
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{{Structure
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|PDB= 2pit |SIZE=350|CAPTION= <scene name='initialview01'>2pit</scene>, resolution 1.76&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene> and <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID'>4HY</scene>
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|ACTIVITY=
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|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Androgen receptor LBD with small molecule'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2PIT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=DHT:'>DHT</scene> and <scene name='pdbligand=4HY:'>4HY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PIT OCA].
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2PIT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PIT OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hormone receptor]]
[[Category: hormone receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:29:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:13:30 2008''

Revision as of 16:13, 20 March 2008


PDB ID 2pit

Drag the structure with the mouse to rotate
, resolution 1.76Å
Ligands: , and
Gene: AR, DHTR, NR3C4 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Androgen receptor LBD with small molecule


Disease

Known diseases associated with this structure: Androgen insensitivity OMIM:[313700], Breast cancer, male, with Reifenstein syndrome OMIM:[313700], Hypospadias, perineal OMIM:[313700], Prostate cancer OMIM:[313700], Prostate cancer, susceptibility to OMIM:[313700], Spinal and bulbar muscular atrophy of Kennedy OMIM:[313700]

About this Structure

2PIT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:13:30 2008

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