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3wsx
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==SorLA Vps10p domain in ligand-free form== |
| - | + | <StructureSection load='3wsx' size='340' side='right' caption='[[3wsx]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3wsx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wsy|3wsy]], [[3wsz|3wsz]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wsx RCSB], [http://www.ebi.ac.uk/pdbsum/3wsx PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SORL_HUMAN SORL_HUMAN]] Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kitago, Y]] | ||
| + | [[Category: Nagae, M]] | ||
| + | [[Category: Nakata, Z]] | ||
[[Category: Nogi, T]] | [[Category: Nogi, T]] | ||
[[Category: Takagi, J]] | [[Category: Takagi, J]] | ||
| - | [[Category: | + | [[Category: Beta-propeller]] |
| - | [[Category: | + | [[Category: Protein binding]] |
| - | [[Category: | + | [[Category: Receptor]] |
Revision as of 15:53, 7 February 2015
SorLA Vps10p domain in ligand-free form
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Categories: Kitago, Y | Nagae, M | Nakata, Z | Nogi, T | Takagi, J | Beta-propeller | Protein binding | Receptor
