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2pmx

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[[Image:2pmx.gif|left|200px]]<br /><applet load="2pmx" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2pmx.gif|left|200px]]
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caption="2pmx, resolution 2.270&Aring;" />
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'''Human K-Ras in complex with a GTP analogue'''<br />
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{{Structure
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|PDB= 2pmx |SIZE=350|CAPTION= <scene name='initialview01'>2pmx</scene>, resolution 2.270&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene> and <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
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|ACTIVITY=
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|GENE= KRAS, KRAS2, RASK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Human K-Ras in complex with a GTP analogue'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2PMX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=GNP:'>GNP</scene> and <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMX OCA].
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2PMX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMX OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: cancer]]
[[Category: cancer]]
[[Category: gtp analogue]]
[[Category: gtp analogue]]
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[[Category: mutations]]
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[[Category: mutation]]
[[Category: sgc]]
[[Category: sgc]]
[[Category: small gtpase]]
[[Category: small gtpase]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:31:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:15:01 2008''

Revision as of 16:15, 20 March 2008

Image:2pmx.gif


PDB ID 2pmx

Drag the structure with the mouse to rotate
, resolution 2.270Å
Ligands: , and
Gene: KRAS, KRAS2, RASK2 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Human K-Ras in complex with a GTP analogue


Disease

Known diseases associated with this structure: Bladder cancer OMIM:[190070], Breast cancer, somatic OMIM:[190070], Costello syndrome OMIM:[190070], Leukemia, acute myelogenous OMIM:[190070], Lung cancer OMIM:[190070], Noonan syndrome 3 OMIM:[190070], Pancreatic carcinoma, somatic OMIM:[190070], Stomach cancer OMIM:[190070]

About this Structure

2PMX is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:15:01 2008

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